Ukulungiswa kwe-procaine & procaine hcl

Isisekelo se-procaine

CAS: 59-46-1

Ukubukeka: i-crystalline powder emhlophe

Iphuzu elincibilikayo (iphuzu elibilayo): 59 ~ 62 ℃

Ifomula yemolekyuli: c13h2on2o2

Isisindo se-molecule: 236.31

I-Procaine hcl

CAS: 51-05-8

Ku-250ml yeflask enezintamo ezintathu ene-stirrer ne-thermometer, ingxube ye-nitrocaine ene-pH engu-4.0-4.2 iyengezwa.Ngaphansi kokunyakaziswa okugcwele, impushana yensimbi ecushiwe yengezwa ku-25 ℃ izikhathi eziningana.Ngemuva kokwengeza, izinga lokushisa lokuphendula liyakhuphuka ngokuzenzakalelayo futhi ligcine ama-40-45 ℃.Isikhathi sokuphendula sasingamahora angu-2.Ngemuva kokuhlunga, insalela yesihlungi igezwa kabili ngamanzi amancane, isisombululo sokugeza sihlanganiswe ne-filtrate, i-acidified ku-pH 5 nge-dilute hydrochloric acid (10%), kanye nesisombululo esigcwele se-sodium sulfide sengezwe ku-pH 7.8- 8.0 ukuze kuncishiswe usawoti wensimbi esixazululweni sokusabela.I-filtrate i-acidified ku-ph6 ngenani elincane le-dilute hydrochloric acid, bese ishiswa ku-50-60 ℃ imizuzu engu-10 ngenani elincane lekhabhoni ecushiwe.Izinsalela zokuhlunga zigezwa kanye ngamanzi amancane, isixazululo sokugeza sihlanganiswe ne-filtrate, sipholile sibe ngaphansi kuka-10 ℃, futhi i-alkalized nge-20% NaOH kuze kube yilapho i-procaine ihlukaniswa ngokuphelele (pH 9.5-10.5).Hlunga, geza kabili, cindezela futhi ukhiphe ukuze wenze usawoti (procaine hcl)